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240 results

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Page 1
Biocatalytic synthesis of oxa(thia)diazole aryl thioethers.
Mottaghi Amlashi D, Mobini S, Shahedi M, Habibi Z, Bavandi H, Yousefi M. Mottaghi Amlashi D, et al. Sci Rep. 2024 Aug 22;14(1):19468. doi: 10.1038/s41598-024-70239-3. Sci Rep. 2024. PMID: 39174618 Free PMC article.
A novel approach for the synthesis of 1,3,4-oxa(thia)diazole aryl thioethers through a biocatalytic strategy has been introduced. ...Using this approach, 13 new derivatives of 2,5-disubstituted-1,3,4-oxa(thia)diazole aryl thioethers, with a yield of 46-94%, were syn …
A novel approach for the synthesis of 1,3,4-oxa(thia)diazole aryl thioethers through a biocatalytic strategy has been introduced. ... …
Nanoliposomal oxaliplatin ameliorates chemotherapy-induced neuropathy.
Alaei M, Moetamani-Ahmadi M, Mahaki H, Fiuji H, Maftooh M, Hassanian SM, Khazaei M, Shahri AP, Ferns GA, Frozanfar F, Tanzadehpanah H, Avan A. Alaei M, et al. Neurosci Lett. 2023 Aug 24;812:137367. doi: 10.1016/j.neulet.2023.137367. Epub 2023 Jul 5. Neurosci Lett. 2023. PMID: 37419304
Chemotherapy-induced peripheral neuropathy (CIPN) is an important adverse effect of treatment with oxaliplatin (OXA). We have developed PEGylated nanoliposomal oxaliplatin (OXA-LIP) and tested its activity in an animal model of CIPN. ...OXA had a significantl …
Chemotherapy-induced peripheral neuropathy (CIPN) is an important adverse effect of treatment with oxaliplatin (OXA). We have develop …
Water-Promoted Ir-Catalyzed Ring-Opening of Oxa(aza)benzonorbornadienes with Fluoroalkylamines.
Yang X, Yang W, Yao Y, Deng Y, Zuo X, Yang D. Yang X, et al. J Org Chem. 2018 Sep 7;83(17):10097-10106. doi: 10.1021/acs.joc.8b01396. Epub 2018 Jul 24. J Org Chem. 2018. PMID: 30040416
A highly effective water-promoted iridium-catalyzed ring-opening reaction of oxa(aza)benzonorbornadienes with fluoroalkylamines was developed for the synthesis of fluorinated trans-1,2-amino alcohol or diamine derivatives. Tetrabutylammonium iodide (TBAI) was necessary as …
A highly effective water-promoted iridium-catalyzed ring-opening reaction of oxa(aza)benzonorbornadienes with fluoroalkylamines was d …
Design and Synthesis of Chiral oxa-Spirocyclic Ligands for Ir-Catalyzed Direct Asymmetric Reduction of Bringmann's Lactones with Molecular H(2).
Chen GQ, Lin BJ, Huang JM, Zhao LY, Chen QS, Jia SP, Yin Q, Zhang X. Chen GQ, et al. J Am Chem Soc. 2018 Jul 5;140(26):8064-8068. doi: 10.1021/jacs.8b03642. Epub 2018 Jun 25. J Am Chem Soc. 2018. PMID: 29920089
We herein present a facile and column-free synthetic route toward a structurally unique oxa-spirocyclic diphenol, termed as O-SPINOL. Features of the synthesis include the construction of the all-carbon quaternary center at an early stage, a key double intramolecular S(N)A …
We herein present a facile and column-free synthetic route toward a structurally unique oxa-spirocyclic diphenol, termed as O-SPINOL. …
OXA-CuS@UiO-66-NH(2) as a drug delivery system for Oxaliplatin to colorectal cancer cells.
Gholami M, Hekmat A, Khazaei M, Darroudi M. Gholami M, et al. J Mater Sci Mater Med. 2022 Feb 28;33(3):26. doi: 10.1007/s10856-021-06574-y. J Mater Sci Mater Med. 2022. PMID: 35226206 Free PMC article.
The CuS nanoparticles (NPs) were prepared to enhance the anticancer effects of Oxaliplatin (OXA) against colorectal cancer. The oxaliplatin was loaded into CuS@UiO-66-NH(2). To characterize and investigate their cytotoxicity effects, powder X-ray diffraction (PXRD), Fourie …
The CuS nanoparticles (NPs) were prepared to enhance the anticancer effects of Oxaliplatin (OXA) against colorectal cancer. The oxali …
One-pot three-component synthesis of azaspirononatriene derivatives.
Oudi A, Esmaeili AA, Habibi A. Oudi A, et al. Sci Rep. 2025 Apr 30;15(1):15174. doi: 10.1038/s41598-025-97860-0. Sci Rep. 2025. PMID: 40307286 Free PMC article.
The coupling reaction between the "in situ" generated dipoles of the isocyanide-acetylenic ester adducts and 3-alkyl-4-arylidene-isoxazol-5(4H)-one derivative presents a highly effective synthetic pathway for obtaining novel 1-oxo-2-oxa-3-azaspiro[4.4]nona-3,6,8-triene het …
The coupling reaction between the "in situ" generated dipoles of the isocyanide-acetylenic ester adducts and 3-alkyl-4-arylidene-isoxazol-5( …
Orexin A and B in the rat superior salivatory nucleus.
Sato T, Yajima T, Fujita M, Kobashi M, Ichikawa H, Yoshida R, Mitoh Y. Sato T, et al. Auton Neurosci. 2020 Nov;228:102712. doi: 10.1016/j.autneu.2020.102712. Epub 2020 Jul 21. Auton Neurosci. 2020. PMID: 32721850 Free article.
OXA- and OXB-immunoreactive (-ir) nerve fibers were seen throughout the SSN. These nerve fibers surrounded SSN neurons retrogradely labeled with Fast blue (FB) from the corda-lingual nerve. FB-positive neurons had pericellular OXA- (47.5%) and OXB-ir ( …
OXA- and OXB-immunoreactive (-ir) nerve fibers were seen throughout the SSN. These nerve fibers surrounded SSN neurons retrogr …
High Frequency of bla(OXA-48like) Producing Klebsiella pneumoniae Isolated from Nosocomial Infection in Azerbaijan, Iran.
Ghotaslou R, Salahi B, Naderi G, Alizadeh N. Ghotaslou R, et al. Infect Chemother. 2023 Mar;55(1):90-98. doi: 10.3947/ic.2022.0160. Infect Chemother. 2023. PMID: 37021426 Free PMC article.
The most common carbapenemases gene in CRKP isolates were bla(OXA-48-like) (76%) followed by bla(NDM) (50%), bla(IMP) (22%), bla(VIM) (10%), and bla(KPC) (10%). ...CONCLUSION: The bla(OXA-48-like) is the main carbapenemase among CRKP isolates in this area. Most bla( …
The most common carbapenemases gene in CRKP isolates were bla(OXA-48-like) (76%) followed by bla(NDM) (50%), bla(IMP) (22%), bla(VIM) …
The context of bla(OXA-23) gene in Iraqi carbapenem-resistant Acinetobacter baumannii isolates belonging to global clone 1 and global clone 2.
Wajid Odhafa M, Al-Kadmy I, Pourmand MR, Naderi G, Asadian M, Ghourchian S, Douraghi M. Wajid Odhafa M, et al. BMC Res Notes. 2024 Oct 8;17(1):300. doi: 10.1186/s13104-024-06890-w. BMC Res Notes. 2024. PMID: 39380025 Free PMC article.
The global clones (GC) and the genes encoding carbapenem resistance, including bla(OXA-23), bla(OXA-24), and bla(OXA-58) were identified using multiplex PCR assays. Antibiotic susceptibility testing was performed by the Kirby-Bauer disk diffusion susceptibili …
The global clones (GC) and the genes encoding carbapenem resistance, including bla(OXA-23), bla(OXA-24), and bla(OXA-58 …
240 results