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Page 1
Did you mean aras n (98 results)?
AlphaFold2 structures guide prospective ligand discovery.
Lyu J, Kapolka N, Gumpper R, Alon A, Wang L, Jain MK, Barros-Álvarez X, Sakamoto K, Kim Y, DiBerto J, Kim K, Glenn IS, Tummino TA, Huang S, Irwin JJ, Tarkhanova OO, Moroz Y, Skiniotis G, Kruse AC, Shoichet BK, Roth BL. Lyu J, et al. Science. 2024 Jun 21;384(6702):eadn6354. doi: 10.1126/science.adn6354. Epub 2024 Jun 21. Science. 2024. PMID: 38753765 Free PMC article.
An open-source drug discovery platform enables ultra-large virtual screens.
Gorgulla C, Boeszoermenyi A, Wang ZF, Fischer PD, Coote PW, Padmanabha Das KM, Malets YS, Radchenko DS, Moroz YS, Scott DA, Fackeldey K, Hoffmann M, Iavniuk I, Wagner G, Arthanari H. Gorgulla C, et al. Nature. 2020 Apr;580(7805):663-668. doi: 10.1038/s41586-020-2117-z. Epub 2020 Mar 9. Nature. 2020. PMID: 32152607 Free PMC article.
TRPC5.
Zholos AV. Zholos AV. Handb Exp Pharmacol. 2014;222:129-56. doi: 10.1007/978-3-642-54215-2_6. Handb Exp Pharmacol. 2014. PMID: 24756705 Review.
TRPC5 has a distinct voltage dependence shared only with its closest relative, TRPC4. Its unique N-shaped activation curve underlined by intracellular Mg(2+) block seems to be perfectly "shaped" to trigger action potential discharge, but not to grossly interfere with the a …
TRPC5 has a distinct voltage dependence shared only with its closest relative, TRPC4. Its unique N-shaped activation curve underlined …
Control of B-1a cell development by instructive BCR signaling.
Kreslavsky T, Wong JB, Fischer M, Skok JA, Busslinger M. Kreslavsky T, et al. Curr Opin Immunol. 2018 Apr;51:24-31. doi: 10.1016/j.coi.2018.01.001. Epub 2018 Feb 3. Curr Opin Immunol. 2018. PMID: 29414528 Free PMC article. Review.
Arylboration of Enecarbamates for the Synthesis of Borylated Saturated N-Heterocycles.
Trammel GL, Kannangara PB, Vasko D, Datsenko O, Mykhailiuk P, Brown MK. Trammel GL, et al. Angew Chem Int Ed Engl. 2022 Nov 14;61(46):e202212117. doi: 10.1002/anie.202212117. Epub 2022 Oct 17. Angew Chem Int Ed Engl. 2022. PMID: 36250954 Free PMC article.
Two catalytic systems have been developed for the arylboration of endocyclic enecarbamates to deliver synthetically versatile borylated saturated N-heterocycles in good regio- and diastereoselectivities. A Cu/Pd dual catalytic reaction enables the synthesis of borylated, a …
Two catalytic systems have been developed for the arylboration of endocyclic enecarbamates to deliver synthetically versatile borylated satu …
Peripheral N-methyl-D-aspartate receptor localization and role in gastric acid secretion regulation: immunofluorescence and pharmacological studies.
Golovynska I, Beregova TV, Falalyeyeva TM, Stepanova LI, Golovynskyi S, Qu J, Ohulchanskyy TY. Golovynska I, et al. Sci Rep. 2018 May 10;8(1):7445. doi: 10.1038/s41598-018-25753-6. Sci Rep. 2018. PMID: 29749407 Free PMC article.
The enteric nervous system (ENS) and a glutamate receptor (GluR), N-methyl-D-aspartate receptor (NMDAR), participate in gastric acid secretion (GAS) regulation. ...
The enteric nervous system (ENS) and a glutamate receptor (GluR), N-methyl-D-aspartate receptor (NMDAR), participate in gastric acid …
Docking for EP4R antagonists active against inflammatory pain.
Gahbauer S, DeLeon C, Braz JM, Craik V, Kang HJ, Wan X, Huang XP, Billesbølle CB, Liu Y, Che T, Deshpande I, Jewell M, Fink EA, Kondratov IS, Moroz YS, Irwin JJ, Basbaum AI, Roth BL, Shoichet BK. Gahbauer S, et al. Nat Commun. 2023 Dec 6;14(1):8067. doi: 10.1038/s41467-023-43506-6. Nat Commun. 2023. PMID: 38057319 Free PMC article.
Expanding the chemical space of 3(5)-functionalized 1,2,4-triazoles.
Khomenko DM, Doroshchuk RO, Ohorodnik YM, Ivanova HV, Zakharchenko BV, Raspertova IV, Vaschenko OV, Dobrydnev AV, Grygorenko OO, Lampeka RD. Khomenko DM, et al. Chem Heterocycl Compd (N Y). 2022;58(2-3):116-128. doi: 10.1007/s10593-022-03064-z. Epub 2022 Mar 23. Chem Heterocycl Compd (N Y). 2022. PMID: 35340781 Free PMC article.
77 results